| 產品編號 | bs-42307P |
| 英文名稱 | Recombinant human CLDN1 protein, N-Trx-His |
| 中文名稱 | 人緊密連接蛋白1重組蛋白 |
| 別 名 | CLD1_HUMAN; Claudin-1; Claudin 1; Claudin1; CLD1; SEMP1; Senescence-associated epithelial membrane protein; UNQ481/PRO944; ILVASC. |
| 理論分子量 | 23.6kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | >1mg/ml |
| 物 種 | Human |
| 序 列 | 137-211/211 |
| 純 度 | >90% as determined by SDS-PAGE |
| 純化方法 | AC |
| 內毒素 | Not analyzed |
| 表達系統(tǒng) | E.coli |
| 標簽 | N-Trx-His |
| 緩 沖 液 | 20mM Tris-Hcl (pH=8.0) |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產品介紹 | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008] SWISS: O88551 Gene ID: 12737 Claudin 1蛋白是緊密連接區(qū)相關的轉膜蛋白Claudin的家族成員，在構成緊密連接的完整膜蛋白中發(fā)揮著一定作用，目前多用于腫瘤方面的研究。 |
| 產品圖片 |  The purity of the protein is greater than 90% as determined by reducing SDS-PAGE. |
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